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ABOUT FIB

This netcast explores the rapidly changing world of biotech, with a penchant towards getting a better understanding of who we are and where we are going. The living world will soon be a true substrate for engineering. Our world will change, and so will we. 

We bring a first hand account from the scientists that are moving us into this new technological era: the era of biotech.


Produced by TWiT.Tv

 

 

 

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    Saturday
    Nov192011

    Towards Curing Malaria With Dr. Elizabeth Winzeler

     

    Host: Marc Pelletier

    Guest: Dr. Elizabeth Winzeler, Ph.D.; Department Head, Department of Cellular Biology, Genomics Institute of the Novartis Research Foundation, San Diego, CA' Associate Professor, Department of Cell Biology, The Scripps Research Institute, La Jolla, CA

    In this episode, Dr. Elizabeth Winzeler shares her strategy to tackle malaria, a disease that affects 250-500 million people per year.

    Link to Dr. Winzeler's paper

    More information

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    Saturday
    Nov052011

    Futures in Biotech 88: Cogito, Ergo Sum... Multitasking?

    How understanding our mind will shape our futures with Dr. Adam Gazzaley.

    Hosts: Marc Pelletier, Ph.D. and Dave Brodbeck, Ph.D.
    Guest: Adam Gazzaley, M.D., Ph.D.

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    Saturday
    Nov052011

    Futures in Biotech 87: Anti-Matter Message In A Magnetic Bottle


    Host: Marc Pelletier

    We talk with Professor Jeffrey Hangst of the ALPHA Collaboration about the successful trapping of anti-hydrogen to hopefully answer some of our most important questions about the universe.

    Guest: Prof. Jeffrey Hangst

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    Monday
    Oct032011

    Futures in Biotech 87: Anti-Matter Message In A Magnetic Bottle

    VIDEO COMING SOON

    Host: Marc Pelletier

    We talk with Professor Jeffrey Hangst of the ALPHA Collaboration about the successful trapping of anti-hydrogen to hopefully answer some of our most important questions about the universe.

    Guest: Prof. Jeffrey Hangst 

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    Monday
    Oct032011

    Futures in Biotech 86: Biomasses For The Masses

    Host: Marc Pelletier

    Changing an Amish farm in Ohio into an energy source solution for modern times. The story of the Griswold family and Altoterra Energy.

    Guests: John Griswold , Matthew J. Griswold, CFA and Mark A. Griswold, Ph.D.

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    Sunday
    Aug212011

    Futures in Biotech 85: Modeling Life With The World's Most Powerful Computer System

    Host: Marc Pelletier

    Dr. Vijay Pande, Stanford's Director of Folding@home, details how the world's most powerful system models Alzheimer's and other human diseases.

    Guest: Dr. Vijay Pande

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    Sunday
    Aug212011

    Futures in Biotech 84: Biotech - Hot in Cleveland

    Host: Marc Pelletier

    Baiju Shah, President & CEO of BioEnterprise, explains how to transform a regional economy into a thriving biotechnological innovation center.

    Guest: Baiju Shah, J.D.

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    Saturday
    Jul092011

    Futures in Biotech 83: Bioinformatics: Essential Gene names Skewed in a Network of Blame

    Host: Marc Pelletier

    Guest: Mark Gerstein

    Dr. Mark Gerstein from Yale University explains the essence of life through network theory.

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    SLIDES HERE: Biological Network Analysis

    Monday
    Jun272011

    Futures In Biotech 82: Bionic Brain Symbionts: The Next Phage of Human Slurry

    Hosts: Drs. Marc Pelletier, Andre Nantel, and Justin C. Sanchez

    We discuss Justin's work on brain machine symbiotic devices, to identifying the key elements in autoimmune disease, to the race between transcription and translation; it's genetics gone wild.

    Papers discussed:

    1) First cystic fibrosis drug advances towards approval (2011). Nature Biotechnology 29:465-466

     

    2) A symbiotic brain-machine interface through value-based decision making.

    Mahmoudi B, Sanchez JC.

    PLoS One. 2011 Mar 14;6(3):e14760.

    3) Autoantigen discovery with a synthetic human peptidome.

    Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ.

    Nat Biotechnol. 2011 May 22;29(6):535-41. doi: 10.1038/nbt.1856.

    4) Global quantification of mammalian gene expression control.

    Schwanhäusser B, Busse D, Li N, Dittmar G, Schuchhardt J, Wolf J, Chen W, Selbach M.

    Nature. 2011 May 19;473(7347):337-42.

    Friday
    Jun172011

    Futures in Biotech 81: Worm Research: The Buck Starts Here

    Hosts: Marc Pelletier and Simon Melov

    Guest: Gordon Lithgow, Ph.D., professor at the Buck Institute for Research in Aging

    Dr. Gordon Lithgow bridges the science of protein folding and life extenstion. The paper that we discuss:

    Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan.

    Alavez SVantipalli MCZucker DJKlang IMLithgow GJ.

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    Friday
    Jun172011

    Futures In Biotech 80: Light Up The Brain

    Host: Marc Pelletier and Special Guest Host Dave Brodbeck, PhD

    Using optogenetics to study learning and cognition.

    Guest: Dr. Ann M. Graybiel

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    Friday
    Jun172011

    Futures In Biotech 79: Oceans 20

    Host: Marc Pelletier and Special Guest Host Mark Gerstein

    A test run for the technology that will transition us into the next era of medicine: Proteomics.

    Guest: Dr. Tommy Nilsson

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    Thursday
    May122011

    Futures in Biotech 78: TWiV Infects FiB

     

     

    Hosts: Marc Pelletier and Vincent Racaniello

    It's a science mashup. FiB and TWiV together for one big show.

    Guests: Dickson Despommiers, Ph.D. , Alan Dove, Ph.D. and Richard Condit , Ph.D.

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    Tuesday
    Mar152011

    Must See: Cassini Images Made into a Film.

    Sunday
    Mar132011

    Futures in Biotech 77: How the Environment and a Single Protein Influence Evolution

    Hosts: Marc Pelletier 

    Drs. Susan Linquist and Daniel Jarosz explain how the environment can drive evolution at the molecular level.

    Guests: Susan Lindquist, Ph.D. and Daniel Jarosz, Ph.D.

    PAPER PRESENTED:

    Science. 2010 Dec 24;330(6012):1820-4.

    Hsp90 and environmental stress transform the adaptive value of natural genetic variation.

    Jarosz DFLindquist S.

    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

    Abstract

    How can species remain unaltered for long periods yet also undergo rapid diversification? By linking genetic variation to phenotypic variation via environmental stress, the Hsp90 protein-folding reservoir might promote both stasis and change. However, the nature and adaptive value of Hsp90-contingent traits remain uncertain. In ecologically and genetically diverse yeasts, we find such traits to be both common and frequently adaptive. Most are based on preexisting variation, with causative polymorphisms occurring in coding and regulatory sequences alike. A common temperature stress alters phenotypes similarly. Both selective inhibition of Hsp90 and temperature stress increase correlations between genotype and phenotype. This system broadly determines the adaptive value of standing genetic variation and, in so doing, has influenced the evolution of current genomes.

    PHOTO CONTEST:

     

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    Sunday
    Feb272011

    Futures In Biotech 76: It's Time To Proteo Me

    Tuesday
    Feb222011

    Futures In Biotech 75: It's Time To Start The Human Proteome

    Host: Marc Pelletier

    Our guests talk about the next big transition in modern medicine: Human Proteomics.

    Guests: Dr. John Bergeron and Dr. Tommy Nilsson

    Sponsored by: Synergy 1.

    We invite you to read, add to, and amend our show notes

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    Thursday
    Jan272011

    In the news...

    Saturday
    Jan152011

    Futures in Biotech 74: Cancer and Aging: Rival Demons with Dr. Judith Campisi 

    Hosts: Marc Pelletier and Simon Melov

    Dr. Judith Campisi's scientific investigations are at the nexus between cancer and aging. She seeks to better understand how cellular senescence contributes to the pathophysiology of aging.

    Guest: Dr. Judith Campisi, Ph.D., Professor at the Buck Institute; Senior Scientist, Lawrence Berkeley National Laboratory.

    Sponsored by: Synergy 1.

    We invite you to read, add to, and amend ourshow notes.

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    Thursday
    Jan132011

    Futures in Biotech 73: Age Research with Brian Kennedy

    Hosts: Marc Pelletier, Simon Melov, Ph.D.

    We will discuss the biotech of life extension with the scientist that discovered the Sirtuan family of genes.

    Guest: Brian Kennedy, Ph.D.: President and CEO, Buck Institute for Age Research.

    We invite you to read, add to, and amend our show notes.

    Comments and suggestions on Futures in Biotech.

    Sponsored by: Synergy 1 & Mailroute

    Thanks to Cachefly for providing the bandwidth for this netcast.

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