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This netcast explores the rapidly changing world of biotech, with a penchant towards getting a better understanding of who we are and where we are going. The living world will soon be a true substrate for engineering. Our world will change, and so will we. 
We bring a first hand account from the scientists that are moving us into this new technological era: the era of biotech. 

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    FiB Episode 022 - Metabolic Engineering and the Marathon Mouse with Dr. Ron Evans

    Dr. Ron Evans discusses the genetic engineering of metabolism and the creation of a strain of super mice: the Marathon Mouse

    Host: Marc Pelletier

    Guest: Dr. Ron Evans, Professor and the March of Dimes Chair in Molecular and Developmental Biology, Salk Institute.

    In this episode, Dr. Evans talks about science in a very pure sense and explains his approach to asking the right questions. This can truly make or break a scientist. He also talks about the great experience and people he has met while working at the Salk Institute, his pioneering work on cloning the growth hormone gene, and lastly, how his discoveries have led to the engineering the Marathon Mouse -the first example of the metabolic engineering of endurance.

    Imagine having the conditioning and fat burning metabolism of a long distance runner without exercise (or for those that can't exercise), or on the other side the coin, being able to run long distances without prior training... Most importantly here, the Marathon Mouse provides proof-of-concept that metabolism can be controlled, and the potential medical benefits seem almost countless.

    Some interesting links:

    Howard Hughes Medical Institute
    Life in the lab
    'Exercise Pill'


    References (4)

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