Futures In Biotech 76: It's Time To Proteo Me

Hosts: Marc Pelletier and Vincent Racaniello

How mass spectrometry has become one of the most important technologies in our move toward personalized medicine.

Guest: Prof. Ruedi Aebersold

Sponsored by: Synergy 1.

PAPERS DISCUSSED:

Comprehensive quantitative analysis of central carbon and amino-acid metabolism in Saccharomyces cerevisiae under multiple conditions by targeted proteomics.

Costenoble R, Picotti P, Reiter L, Stallmach R, Heinemann M, Sauer U, Aebersold R.

Mol Syst Biol. 2011 Feb 1;7:464.

Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.

Bodenmiller B, Wanka S, Kraft C, Urban J, Campbell D, Pedrioli PG, Gerrits B, Picotti P, Lam H, Vitek O, Brusniak MY, Roschitzki B, Zhang C, Shokat KM, Schlapbach R, Colman-Lerner A, Nolan GP, Nesvizhskii AI, Peter M, Loewith R, von Mering C, Aebersold R.

Sci Signal. 2010 Dec 21;3(153):rs4.

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